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Monthly Archives: February 2021

Scalable computer software platform conducts integrative single-cell chromatin accessibility analysis

A crew of scientists from Stanford University, functioning with associates from your Gladstone Institute of data Science and Biotechnology and King Abdulaziz University

They has established a software package platform which will be utilized for integrative single-cell chromatin accessibility investigation. Inside their capstone in nursing school paper released while in the journal Mother nature Genetics, the group describes the software system, the platforms on which it might be run, and just how it would be utilized by scientists.

Currently, scientists are able to create extremely big datasets that contains information regarding single-cell chromatin, the fabric that makes up chromosomes, these kinds of as DNA and RNA. Sadly, equipment that make it easy for for examining these types of info are limited. One in all the principle difficulties would be the amount of further data that is developed as part of such analyses?it grows at these a rate that it overwhelms pc memory. In this new work, the scientists have triumph over that issue along with the improvement of a new software product called ArchR.

The new software programs is geared towards investigation involving the best way that genes are regulated with the physical arrangement of DNA. ArchR may be used to research single-cell details on chromatin accessibility?it reveals the ways in which DNA is often concerned with transcription. Extra exclusively, it might be accustomed to analyze single-cell clustering, double removal, mobile trajectory identification and unified peak set generation.

Making the applications all the more beneficial is usually that it can operate without the will need to get a high-performance pc. The researchers for the undertaking also claim that it’s got an easy-to-use interface that for finishing up many different examination eventualities. In addition they claim which the new program runs a few of the very same different kinds of analysis schemes as other systems, but faster. And many importantly, owing to the way it had been designed, memory challenges will no more be described as a trouble. Testing showed it capable of functioning with much larger datasets than latest devices.

The researchers take note which the new strategy provides a simpler solution to mix transcriptome and epigenome analyses. They advise that their new software program has functional apps for scientists within the discipline. They subsequent arrange to add alot more functionality with the product.

In current several years, energetic, self-propelled particles have gained growing desire among the scientific community

Examples of lively particles as well as their methods are numerous and really varied, ranging from bacterium movies to flocks of birds or human crowds. These methods can exhibit strange actions, which is certainly tricky to grasp or model.To this finish, large-scale designs of energetic particles were becoming scrutinized by industry professionals at Leicester, for you to fully grasp basic principles fundamental energetic particle dynamics and apply them inside a scenario of an evacuation methodology for customers inside of a crowded put. Unexpectedly, the ‘super-particles’ milling inside a circular motion had been stumbled upon by Leicester’s physicists who subsequently coined the phenomenon as ‘swirlonic.’

The ‘swirlon’?a novel state of energetic matter?displayed a stunning habits whereby as a substitute for going with acceleration, the quasi-particle groups moved which includes a consistent velocity, proportional for the utilized force and in similar path of your force. This conduct seemingly violates the next Newton’s Legislation, at the moment taught in secondary schools through the United kingdom.

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A comparison of On-line Online dating services

Text exists beneath the Creative Commons Attribution-ShareAlike License; additionally terms may apply. Through the use of this site, you adapt the Terms of Use and Privacy Policy. Wikipedia® is a documented trademark of the Wikimedia Basis, Inc., a non-revenue group. AdultFriendFinder Ideal for exploring fetishes and numerous on the net preparations, AdultFriendFinder. com is essential for those planning to heat some misconception on-line. OnlineBootyCall As you might expect, OnlineBootyCall is perfect for booty telephone calls. With an enormous affiliate base and acquainted features, XMatch. com is actually a dependable place to go for those seeking a fast interconnection. With lots of eye-sweet to get you launched, that is you for the books.

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It doesn’t matter when you aren’t into long-term internet dating, however the recommendations remain the same. Read suggestions from previously users just before using a practical dating application. These, and even more, are a range of the things you must consider, similar to with long-time period dating software. Experimenting with unique potential seeing networks can assist territory yourself one of the best dating websites out there. As a result of eHarmony’s app, you rarely need to be taking your PC with you everywhere, given your age. The platform boasts a large user base widening your chances of finding a possible meet. And the fact that the users listed here are sexually productive is a in addition.

What Are The top Dating Sites Meant for Seniors?

Possibly method, that is one of the greatest gender dating websites for youthful men striving to participate with cougars. Founded more than a decade ago, iHookUp can be described as Tinder-style hookup site (not a dating web page, got it? ) created for true romance trying to get lay without any commitment. While iHookUp is especially a desktop focused platform, subscribers are however able to figure out matches of their space, making it straightforward to locate an immediate day nearby. iHookUp allegedly complements its paid members primarily based over a couple of cozy persona issues, however the internet site values physical attraction above mental suitability.

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Perform Individuals Still Use Get together On-line Internet dating sites?

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Alternative. com may be your very best software for meeting up — the majority of members listed below are into BDSM. The website provides millions of clients, too, that serves to have the ability to discover a associate. SilverSingles has an practically equal sexuality proportion, too, increasing your odds of finding various other informal-sex seekers. Almost all of the members happen to be aged 50+, so that you simply knock into matches in your age range, and are educated.

Her: Finest Just for Lgbtq Females

But even though fake profiles exist there, a lot of people have found new good friends, dates, and missed cable connections over time. It truly is harder to locate matches in rural locations where there will be smaller masse. You may want to drive just as much as miles to satisfy up with any match, especially on not as much nicely-identified apps like Total or Love-making Messenger.

This web site is certainly sexually certain, with stay-action cameras, video going, nude images, and crazy discussion board subject matter. Men who have find it not comfortable to achieve to be able to females could recognize this kind of web site’s design.

Zoosk: Best Simple Dating Iphone app

First off, make certain that the placing you are utilizing verifies every customer. This might be described as a easy electronic mail verification or perhaps textual content confirmation. Most of the users on Blendr are newer professionals just on the lookout for a fantastic time. If you are planning to journey the earth and if you’re attempting to have sex, that is the approach to take. To get began all you need is a appear e-mail deal with and a user name.

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The next element you want to look for is the corresponding system. In many instances, dating sites incorporate some type of set of questions that helps you will find like-minded people excited about informal sex. Everything that being referred to, most of these hookup sites and online dating software, have selections for both cellular and computer system. When it requires finding a everyday hookup in your city, there are one million choices to choose from. And when you might have just began informal seeing on-line, you could experience noticed the top choice of hookup websites and apps in existence. On a lot of that, OkCupid is fine for men, females, non-binary and transexual persons.

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Best For Young ladies Hooking Up

Using a huge buyer base of over 30 million effective users, it’s pretty basic to find a particular date regardless of where you are. This kind of choice is usually the unique dating sites on this list. SeekingArrangement can be described as massively in fashion dating website that was made for a extremely particular purpose. Today, Ashley Madison retains a status for affairs, but it’s also a fantastic destination to search out casual, no-strings-attached relationships. Results from the personality quiz plus prompts you answer photos you publish assist guide dialog, so you should have plenty of jumping off factors. But undoubtedly additionally Guided Communication, a 4-step software of interaction together with your complements, when you want somewhat additional help. Basically, it is a series of problems that assist to interrupt ice.

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Overseas Brides Review Helps International Grooms Finds matches With Beautiful Brides to be

Foreign brides are the ones from overseas countries, just like India, Singapore, Malaysia, and the Philippines. They will feature different backgrounds and therefore are eligible to become married inspite of their competition or faith. The best way to make contact with these charming people is to become a foreign bride’s review. They will review different websites and online expertise that help foreign brides find their particular life companions. This helps these people not only to get a partner nevertheless also points out various operations and conditions included in a transaction. Reading these types of reviews help foreign birdes-to-be plan their particular weddings and foreign grooms shop for bridal dresses with regards to future wives.

While reading a foreign bride’s review, one particular gets to learn about all the important information forced to click to read more choose a foreign bride-to-be. Details such as the names from the groom and foreign star of the wedding, country of birth, the proposed marriage date, and other important specifics need to be investigated. A brief history of both the households is also referred to, so that overseas brides have some idea in regards to what to expect inside their fresh life along.

Since the facts available in these kinds of sites will be updated on the timely basis, one can rely on the information available in the review to plan their particular meeting. The review comprises of various methods to approach the bride and also the preparation pertaining to the wedding formal procedure and post-wedding celebrations. One or two examples of the tips included in the review articles include the using of professional photography enthusiasts for the marriage photographs. This kind of saves the bride and groom your time and effort of having to go out and consider their own photos. Other advice on preparing for and conducting a successful wedding involve creating a list of guests for the purpose of the bridal party, learning how to dance the lure in Thai, knowing the proper Buddhist customs to follow at the wedding, and then, preparing for the vacation and beginning a new your life in different urban centers.

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Prevalent Myths About Foreign Brides

Many of the foreign brides which have been considered warm picks intended for the foreign woman have a thing in common. They are via countries which are not exactly recognized for their beauty, just like Russia, Indonesia or Asia. Some of these females do not show up all that attractive in images, but the males who have tried out on these foreign brides to be have been amazed with what they look like. Most of them come in fairly petite packages, as this is one of the requirements in the international birdes-to-be who making the effort to find a spouse from foreign. There are some men who want a larger bride, so if you are taller or have an enormous butt, there are several foreign wedding brides who will appreciate it.

For people who attempt to find love at first base with overseas men, it will help to realize that many men from these types of countries are looking for true love out of someone who is definitely honest and pure. That is not mean that every mail order brides will probably be looking for a romantic relationship that will turn into a marriage, as that happens in under 1% of this marriages that end up in divorce. When you are going out with a man out of another country, it is vital that you trust him totally before you let him find out everything about you. It is important to leave him know that you are open to different cultures and that you hope to finally introduce him to the way of life of your home region as well.

Foreign brides usually want a partner from another type of country, since the cultural exchange is somewhat more interesting and fun. Lots of men from these types of countries need to spend their particular time with someone who differs, so this is definitely not a trait a man in the United States will need to share. You have got to be willing to live together for a while as you get married to a foreign national, and many of such brides are searching for someone who is usually willing to live alone when they are engaged and getting married. There are plenty of international brides so, who choose to live their region, nonetheless there are also numerous others who want to move to these countries. If you are a person who is considering this type of bride, you may want to retain these crucial points at heart.

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Common Myths About Foreign Brides to be

Many try this site of the overseas brides which might be considered sizzling picks pertaining to the foreign bride have something in common. They are out of countries which are not exactly known for their beauty, just like Russia, Indonesia or Thailand. Some of these women do not look all that beautiful in images, but the guys who have tried on these types of foreign brides to be have been amazed with what they look like. Many come in very petite plans, as this is among the requirements with the international birdes-to-be who making the effort to find a hubby from foreign. There are some men who want a greater bride, if you are extra tall or have an enormous butt, there are many foreign birdes-to-be who will appreciate it.

For people who are attempting to find love at first bottom part with international men, it helps to realize that a lot of men from these countries are looking for true love by someone who is usually honest and pure. That is not mean that all of the mail buy brides will probably be looking for a marriage that will become a marriage, since that happens in under 1% of this marriages that end up in divorce. When you are online dating a man from another country, it is important that you trust him totally before you allowed him understand everything about you. It is important to leave him know that you happen to be open to different cultures and that you hope to finally introduce him to the lifestyle of your home nation as well.

Foreign brides generally want a partner from another type of country, as the cultural exchange is far more interesting and fun. Many men from these kinds of countries wish to spend the time with someone who differs from the others, so this is absolutely not a trait that a man from the United States will need to share. You’ll have to be willing to live by themselves for a while when you get married to a foreign national, and many these brides are looking for someone who can be willing to live alone even though they are having a wedding. There are plenty of overseas brides who all choose to stay in their country, nevertheless there are also many others who want to transfer to these countries. If you are a guy who is considering this type of new bride, you may want to continue to keep these crucial points in mind.

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Foreign Brides Review Helps International Grooms Finds matches With Beautiful Birdes-to-be

Foreign birdes-to-be are those from overseas countries, like India, Singapore, Malaysia, as well as the Philippines. They will feature different backgrounds and are generally eligible to end up being married irrespective of their competition or religion. The best way to communicate with these beautiful people is to get a foreign bride’s review. They review several websites and online companies that support foreign birdes-to-be find their life associates. This helps these people not only to look for a partner nonetheless also points out various techniques and conditions utilised in a transaction. Reading these reviews help foreign brides plan their very own weddings and foreign grooms shop for marriage dresses for their future spouses.

While examining a foreign bride’s review, a person gets to learn about all the important information needed to choose a foreign star of the event. Details such as the names of this groom and foreign bride, country of birth, the proposed marriage date, and other important particulars need to be looked into. A brief history of both the young families is also pointed out, so that foreign brides have some idea in regards to what to expect in their fresh life jointly.

Since the information available in these kinds of sites happen to be updated over a timely basis, one can rely on the data available in the review to plan their meeting. The review comes with various simple methods to approach the bride as well as the preparation with regards to the wedding ceremony and post-wedding celebrations. A number of examples of the following tips included in the feedback include the usage of professional professional photographers for the wedding photographs. This saves the bride and groom your energy of having get out and take their own photos. Other advice on preparing for and conducting a good wedding incorporate creating a set of guests to get the wedding party, learning how to party the jig in Thai, knowing the correct Buddhist customs to follow at the wedding, and finally, preparing for the honeymoon and beginning a new lifestyle in different places.

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Overseas Bride Site Reviews

There are several international brides’ site that has produced the process of finding a foreign star of the wedding easier for the man plus the women. The sites are designed with the intention of creating the whole procedure a lot easier, when playing the part of the men and on fault the women. The websites are created to build it easy for any person to simply find a overseas bride. These sites have created a platform you choose to be able to satisfy a foreign bride, marry to her, and in some cases travel to her country of origin. You may select a star of the event who is appropriate for yourself, expectations and personality.

One of the features that a majority of of these sites have is a characteristic called “interview”. This feature allows the members for the site to ask questions regarding anything they may be interested in finding out about foreign brides, such as what their requirements are, what the process would be like for your bride coming from a different nation than yours, what kind of roles do foreign brides to be typically perform and more. You can also ask the web page, a question or two if you are even now unsure of some specifics.

If you are planning on choosing a woman for your wedding, it is important that you may spend enough time in studying the profiles of potential foreign birdes-to-be. Choose a bride that has very similar interests to you personally and one which share your same customs. Try to find a bride who is ready to consider your culture and your language when it comes to the type of bride you plan to have. The reason is , you want to spend your vacation in a place that is because close to residence as possible, specifically since you will be spending a large part of the relationship along with the bride. Spending your honeymoon in a foreign nation is a great idea, but if you select the wrong new bride, it could turn out to be a disaster.

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Researchers create beams of entangled atoms

Heads or tails? If we toss two cash into your air, the end result of 1 coin toss has absolutely nothing to undertake together with the result on the other

Coins are unbiased objects. On this planet of quantum physics, important things are different: Quantum particles will be entangled, by which circumstance they can no longer be regarded as unbiased unique objects, they are able to only be described as one particular joint process.For some time, it has been likely to produce entangled photons?pairs of sunshine particles that shift in 100 % completely different instructions but nonetheless belong jointly. Magnificent results have been completely achieved, for instance on the industry of quantum teleportation or quantum cryptography. Now, a whole new approach has actually been created at TU Wien (Vienna) to produce entangled atom pairs?and not only atoms which are emitted in all directions, but well-defined beams. This was attained when using the allow of ultracold atom clouds in electromagnetic traps.

“Quantum entanglement is among the most significant components of quantum physics,” claims Prof. Jorg Schmiedmayer with the Institute of Atomic and Subatomic Physics at TU Wien. “If particles are entangled with one another, then even when you understand every thing you can find to learn in regards to the overall process, you still can not say anything at all in anyway about just one specific particle. Inquiring in regards to the point out of 1 particular particle helps make no perception, just the on the whole state on the full product is defined.”

There are distinctive ways of making quantum entanglement. To illustrate, medical capstone project ideas unique crystals can be used to develop pairs of entangled photons: a photon with huge vigor is transformed with the crystal into two photons of reduced energy?this is termed “down conversion.” This permits large figures of entangled photon pairs to get produced speedily and easily.Entangling atoms, on the other hand, is way much more troublesome. Particular person atoms can be entangled making use of tricky laser operations?but then you definately only get yourself a single set of atoms. Random processes will also be used to produce quantum entanglement: if two particles communicate with one another inside a suitable way, they’re able to turn into entangled afterwards. Molecules is usually damaged up, constructing entangled fragments. But these procedures can’t be controlled. “In this scenario, the particles go in random directions. But after you do experiments, you choose to have the ability to establish exactly where exactly the atoms are going,” suggests Jorg Schmiedmayer.

Controlled twin pairs could now be manufactured at TU Wien by using a novel trick: a cloud of ultracold atoms is created and held in position by electromagnetic forces on a little chip. “We manipulate these atoms to make certain that they don’t finish up inside point out when using the most affordable feasible stamina, but within a state of higher stamina,” claims Schmiedmayer. From this energized condition, the atoms then spontaneously return towards ground point out together with the cheapest electrical power.

However, the electromagnetic trap is manufactured in such a means that this return on the ground condition is physically unimaginable for your solitary atom?this would violate the conservation of momentum. The atoms can thus only get trasferred for the ground condition as pairs and fly away in reverse directions, to make sure that their complete momentum remains zero. This produces twin atoms that go precisely during the course specified with the geometry within the electromagnetic entice over the chip.

The trap consists of two elongated, parallel waveguides. The pair of twin atoms might have been made inside still left or inside the proper waveguide?or, as quantum physics allows, in both equally at the same time. “It’s much like the well-known double-slit experiment, where you shoot a particle at a wall with two slits,” says Jorg Schmiedmayer. “The particle can go through both of those the still left additionally, the ideal slit at the similar time, powering which it interferes with alone, and this creates wave styles which can be measured.”

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Quantum computing with solitary photons obtaining nearer to reality

One promising process for scalable quantum computing will be to use an all-optical architecture, by which the qubits are represented by photons and manipulated by mirrors and beam splitters. Thus far, researchers annotated bibliography generator apa format have shown this process, termed Linear Optical Quantum Computing, on a especially small scale by performing operations implementing just a couple photons. Within an attempt to scale up this method to larger numbers of photons, researchers inside of a new research have developed a means to thoroughly integrate single-photon resources inside of optical circuits, developing built-in quantum circuits which could allow for for scalable optical quantum computation.

The researchers, Iman Esmaeil Zadeh, Ali W. Elshaari, and coauthors, have printed a paper about the integrated quantum circuits inside of a the latest problem of Nano Letters.

As the scientists demonstrate, one in all the biggest worries facing the conclusion of an effective Linear Optical Quantum Computing system is integrating a number of components that happen to be frequently incompatible with each other onto just one platform. These factors incorporate a single-photon source that include quantum dots; routing equipment including waveguides; gadgets for manipulating photons just like cavities, filters, and quantum gates; and single-photon detectors.

In the new analyze, the scientists have experimentally shown a way for embedding single-photon-generating quantum dots inside nanowires that, consequently, are encapsulated within a waveguide. To accomplish this using the higher precision essential, they used a “nanomanipulator” consisting of the tungsten idea to transfer and align the components. At the time inside the waveguide, single photons could very well be picked and routed to completely different parts within the optical circuit, exactly where sensible operations can in due course be performed.

“We proposed and shown a hybrid treatment for integrated quantum optics that exploits the advantages of high-quality single-photon sources with well-developed silicon-based photonics,” Zadeh, at Delft University of Engineering with the Netherlands, advised “Additionally, this technique, compared with former works, is absolutely deterministic, i.e., only quantum sources with all the chosen houses are built-in in photonic circuits.

“The proposed approach can serve as an infrastructure for utilizing scalable integrated quantum optical circuits, that has likely for most quantum technologies. Also, this platform delivers new applications to physicists for researching sturdy light-matter interaction at nanoscales and cavity QED quantum electrodynamics.”

One on the most significant efficiency metrics for Linear Optical Quantum Computing will be the coupling effectiveness among the single-photon source and photonic channel. A affordable performance signifies photon reduction, which reduces the computer’s reliability. The set-up right here achieves a coupling efficiency of about 24% (and that’s by now taken into consideration superior), and the researchers estimate that optimizing the waveguide layout and content could make improvements to this to 92%.

In addition to strengthening the coupling effectiveness, sooner or later the researchers also organize to show on-chip entanglement, as well as expand the complexity on the photonic circuits and single-photon detectors.

“Ultimately, the aim could be to know a completely integrated quantum network on-chip,” claimed Elshaari, at Delft College of Technological know-how and then the Royal Institute of Technologies (KTH) in Stockholm. “At this minute there are lots of possibilities, and then the industry isn’t really properly explored, but on-chip tuning of sources and technology of indistinguishable photons are amongst the worries to become triumph over.”

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Nuclear physicists around the hunt for squeezed protons

While protons populate the nucleus of every atom during the universe, oftentimes they may be squeezed right into a lesser measurement and slip out of the nucleus for just a romp on their own

Observing these squeezed protons could present distinct insights into the particles that build up our universe.”We were being seeking to squeeze the proton this sort of that its quarks are inside of a small-size configuration. And that’s a fairly difficult element to carry out,” mentioned Holly Szumila-Vance, a Jefferson Lab staff members scientist.

Protons are created of a few quarks bound up with the solid drive. Within an common proton, the strong drive is so good that it leaks out, doing the proton follow other protons and neutrons about it with the nucleus. That is as outlined by school nursing education quantum chromodynamics, or QCD, the theory that describes how quarks along with the robust force interact. In QCD, the powerful drive can be known as the colour power.

However, QCD also predicts which the proton could very well be squeezed this kind of which the quarks end up additional tightly knit?essentially wrapping on their own up so tightly while in the shade drive that it now not leaks out of the proton. When that occurs, the proton now not sticks to other particles and may move freely from the nucleus. This phenomenon is termed “color transparency,” for the reason that proton has become invisible on the color pressure for the particles all over it.

An earlier experiment confirmed shade transparency in less difficult particles product of quarks named pions. Where protons have a few quarks, pions have just two. Also, a second experiment conducted with protons experienced also suggested that protons also might possibly show colour transparency at energies nicely close by of the recently upgraded facility at Jefferson Lab.

The experiment was certainly one of the initial to operate within the Continual Electron Beam Accelerator Facility

“We anticipated to search out the protons squeezed just like the pions,” reported Dipangkar Dutta, a professor at Mississippi Point out College and a spokesperson for your experiment. “But we went to larger and better energies and therefore are however not discovering them.””This was an enjoyable experiment to become part of. It absolutely was the primary experiment to run in Experimental Corridor C just after we upgraded the hall for twelve GeV working,” said Szumila-Vance. “These were the highest-momentum protons measured at Jefferson Lab, together with the highest-momentum protons ever made by electron scattering.”

“At the energies we’re probing, the proton is normally decimated, and you are looking on the debris belonging to the proton,” Dutta spelled out. “But within our circumstance, we want the proton to stay a proton, and the only way that which could occur is that if the quarks form of squeeze with each other, maintain one another a whole lot more tightly to ensure that they could escape together through the nucleus.”

While the nuclear physicists noticed a variety of thousand protons from the experiment, they did not find the tell-tale signals of colour transparency with the new knowledge.

“I assume this tells us which the proton is much more sophisticated than we anticipated,” said Szumila-Vance. “This may be a elementary prediction belonging to the principle. We know that it’s to exist at some substantial power, but just really don’t but know just where which may transpire.”The scientists said the next action could be to much better appreciate the phenomenon in more simple particles wherever it has already been observed, to ensure enhanced predictions could be crafted for more intricate particles, including protons.

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